Our clinical data shows improved outcomes for severe burn patients

American Burn Association Clinical Practice Guidelines on Burn Shock Resuscitation 20241

  • Recommendation for clinicians to consider the use of computer decision support software to guide fluid titration and lower resuscitation fluid volumes

Initial Results of ABA Multi-Center Evaluation on the Effectiveness of Burn Navigator, 286 patients, 20222

Key Findings:

  • Average 4.07 mL/kg/TBSA and 151.48 mL/kg of primary fluids given in first 24 hours
  • When all fluids were considered, the “followed Burn Navigator” group received less than the Ivy Index (250 mL/kg in first 24 hours) and was associated with a decreased incidence of shock
  • Early initiation resulted in lower overall fluid volumes

Original U.S. Army Institute of Surgical Research Burn Center Retrospective Review of 70 patients, J Salinas et al, 20113

Key Findings:

  • 24-hour fluids given reduced from 6.5 to 4.2 mL/kg/TBSA (Total Burned Surface Area)
  • 2.5 fewer ventilator days
  • Mortality decreased from 44% to 29% between groups

U.S. Army Burn Center Retrospective Review of 207 patients, J Salinas et al, 20124

Key Findings:

  • 24-hour fluids given were 3.5 mL/kg/TBSA
  • Mean urine output for initial 24 hours was 55 mL/hr

University of Texas Medical Branch Retrospective Review of 53 patients, G Kramer et al, 2015 (poster presentation)5

Key Findings:

  • Mean 24-hour fluids given reduced from 4.1 to 3.0 mL/kg/TBSA
  • Acceptance of recommendations was 89%
  • Unadjusted mortality rate of 33% in before group, 17% in after group

University of Texas Medical Branch Retrospective Review of 154 patients, J Sheaffer et al, 2017 (oral presentation)6

Key Findings:

  • Acute Kidney Injury incidence reduced from 15% to 6% in first five days (p=.089)

References

  1. Cartotto R, et al. American Burn Association Clinical Practice Guidelines on Burn Shock Resuscitation. J Burn Care Res 2024 May 6;45(3):565-589. doi: 10.1093/jbcr/irad125.
  2. Rizzo JA, Serio-Melvin ML, Coates E, Liu NT, Salinas J. Initial results of the American Burn Association (ABA) Multi-Center evaluation on the effectiveness of the Burn Navigator. Abstract from J Burn Care Res. 2021;42(Supplement 1); doi:10.1093/jbcr/irab032.000.
  3. Salinas J, et al. Computerized decision support system improves fluid resuscitation following severe burns: An original study. Crit Care Med 2011 39(9):2031-8.
  4. Salinas J, et al. Review of Patients Resuscitated Using a Computerized Decision Support System in A Burn Intensive Care Unit. Crit Care Med 2012, 225: Abstract only.
  5. Kramer GC, et al. Computerized Decision Support for Burn Resuscitation. J Burn Care and Research 2015, 36(3): S214
  6. Sheaffer J, et al. Incidence of Acute Kidney Injury in Computerized Decision Support System Guided Fluid Resuscitations, American Burn Association Oral Presentation, 24 March 2017.